autonomic drama
Resources for conditions within autonomic dysfunction


A data-first resource for patients, caregivers, and clinicians navigating autonomic dysfunction without the noise. Each article is based around a specific piece of research.


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Testing & Diagnosis — Study
You Can Have Orthostatic Intolerance Without Tachycardia

You should not be able to simply pass or fail a tilt table test. This paper defines a measurable subtype of OI in patients whose HR and BP look completely normal on standard testing.

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Testing & Diagnosis — Study
Evidence for CO₂ and Brain Perfusion in Dysautonomia Since 1998

Foundational for the CO₂ and perfusion conversation in OI testing, and the fact that it dates to 1998 tells you everything about how long this evidence has been ignored at the clinical level.

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Testing & Diagnosis — Study
Why CO₂ Monitoring Belongs in Orthostatic Testing

A review article that explains in plain, coherent logic why CO₂ monitoring belongs in modern orthostatic testing. Useful for making the case to a clinician.

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Testing & Diagnosis — Study
POTS and HyCH Are the Same Problem With Different Compensations

Frames POTS and HYCH/OCHOS as overlapping rather than distinct, and makes a direct claim about what is actually driving the tachycardia in POTS patients.

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Testing & Diagnosis — Study
Brain Blood Flow Can Fall in POTS Even When CO₂ Is Normal

An important counterweight. Not every case of orthostatic cerebral hypoperfusion is explained by hyperventilation and CO₂ dysregulation. Autoregulation itself can be impaired even in normocapnic POTS.

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